Quotes: MENA   Enter Symbol: NewsLetter: Search: advanced

New study shows how stem cells could be used in facial reconstruction  Join our daily free Newsletter

MENAFN Press - 13/03/2014
No. of Ratings : 0
Add to Mixx!



(MENAFN Press) The effectiveness of human stem cell therapies for facial reconstruction has been investigated in a new study led by Great Ormond Street Hospital (GOSH) and the UCL Institute of Child Health (ICH)



The paper, published in the journal Nanomedicine, shows how stem cells could pose a viable alternative to current approaches to facial cartilage reconstruction such as ear and nose reconstruction.



GOSH has an excellent track record of successfully treating patients born with a malformed or missing ear, a condition known as microtia. The two-stage ear reconstruction takes cartilage from the patient's ribs and from this, a new scaffold is moulded and placed beneath the skin.



Both the clinical and cosmetic results of this procedure have been very good. However, as Patrizia Ferretti, Head of Developmental Biology Unit at the ICH and her co-authors demonstrate in their study, the potential application of human stem cells and tissue engineering could further improve results and would obviate the need for this invasive part of the procedure, which leaves a permanent defect in the donor site.



Dr Ferretti explains, "We used stem cells (hADSCs) harvested from the abdominal tissue of young patients affected by craniofacial conditions to explore, in our laboratories, how these might be used in future surgery. The use of stem cells from the paediatric patients themselves circumvents the issue of rejection and would overcome the need for immunosuppressive therapies.



The study suggests that combining hADSC with POSS-PCU bionano scaffolds can be of great value for several applications. In addition to ear and nose cartilage reconstruction, they could be used, for example, to improve the quality of tracheal transplants.



Scaffold cellularization in vivo (within the body) is a lengthy and uneven process. Hence POSS-PCU scaffolds pre-seeded with autologous hADSCs could help to improve stability, integration and functionality of engineered transplants while avoiding tissue rejection



Neil Bulstrode, Consultant Plastic Surgeon at GOSH and an author on the paper said: "It is such an exciting prospect with regard to the future treatment of these patients and many more. Currently I take the rib cartilage from the chest to make an ear but if we could produce a block of cartilage using stem cells and tissue engineering, this would be the Holy Grail for our field.



GOSH has one of the largest and most experienced paediatric plastic and reconstructive surgery centres anywhere in the world, with the aim of providing clinical excellence in our special areas of expertise which include; craniofacial surgery, cleft lip and palate repair, congenital hand anomalies, ear surgery, vascular anomalies and birthmarks and general plastic and reconstructive surgery



Note to editor



Great Ormond Street Hospital for Children is one of the world's leading centres for treating sick children, with the widest range of specialists under one roof in the UK



With the UCL Institute of Child Health, we are the largest centre for paediatric research outside the US, and play a key role in training children's health specialists for the future



Great Ormond Street Hospital for Children treated over 1400 inpatients and over 9000 outpatients from the Middle East in 2012/13


About Great Ormond Street Hospital for Children
Great Ormond Street Hospital for Children is one of the world's leading centres for treating sick children, with the widest range of specialists under one roof in the UK.With the UCL Institute of Child Health, we are the largest centre for paediatric research outside the US, and play a key role in training children's health specialists for the future.Great Ormond Street Hospital for Children treated over 1400 inpatients and over 9000 outpatients from the Middle East in 2012/13.

 


MENAFN Press




  MENA News Headlines
 Jan 29 2015 - HH the Emir Receives Phone Call from Ban Ki-moonQatar News Agency
(MENAFN - QNA) HH the Emir Sheikh Tamim bin Hamad Al-Thani on Thursday received a phone call from the United Nations Secretary-General, Ban Ki-moon, during which he thanked HH the Emir on the ...

 Jan 29 2015 - Consumer spends on pharma products to increase to Dh5.03b by 2020Khaleej Times
(MENAFN - Khaleej Times) Dubai € Consumer expenditure on pharmaceutical products, medical appliances and equipment in the UAE has experienced a strong increase and is forecast to be valued around ...

 Jan 29 2015 - UAE- Time to put cyber security on top priorityKhaleej Times
(MENAFN - Khaleej Times) Kaspersky lab solutions block millions of attacks across the globe, which clearly indicates that cyber criminals are smart, but not smarter than security providers.This was ...

 Jan 29 2015 - Indian business council honours Emirati businessmenKhaleej Times
(MENAFN - Khaleej Times) Dubai - The Indian Business and Professional Council (IBPC) hosted a reception on the occasion of the 66th Republic Day of India at the Oberoi Hotel, Business Bay, on Sunday. ...

 Jan 29 2015 - UAE, Canada discuss ways to boost tradeKhaleej Times
(MENAFN - Khaleej Times) Abu Dhabi - Abdullah Al Saleh, Undersecretary of the Ministry of Economy for Foreign Trade, received a Canadian delegation led by Martin Zablocki, CEO of the Canadian ...

 Jan 29 2015 - Emirates NBD facilitates Stanbic in $85 million loan facilityKhaleej Times
(MENAFN - Khaleej Times) Al Ahli Bank of Kuwait and Standard Chartered Bank joined the transaction as mandated lead arrangers while Al Khalij Commercial Bank and The Commercial Bank of Qatar ...

 Jan 29 2015 - NBAD profit jumps 28% in 2014Khaleej Times
(MENAFN - Khaleej Times) Abu Dhabi - A strong growth in incomes from interest and non-interest based revenues bolstered the National Bank of Abu Dhabi (NBAD) profits to Dh1.372 billion in the quarter ...

 Jan 29 2015 - UAE pharma spend to hit Dh5 billion by 2020Khaleej Times
(MENAFN - Khaleej Times) It is also forecasted to increase at a compound annual growth rate (CAGR) of about 9.78 per cent from 2014 to 2020 as, by then, the value of consumer expenditure on ...

 Jan 29 2015 - Parents happy with children's educationKhaleej Times
(MENAFN - Khaleej Times) Abu Dhabi: A survey by the Abu Dhabi Education Council (Adec) has revealed that parents across the emirate are satisfied with their children's schools. The education ...

 Jan 29 2015 - Customers continue winning at Malabar Gold 1amp Diamonds FestivalArab News
(MENAFN - Arab News) Customers continue to win at Malabar Gold & Diamonds' ongoing gold and diamond festival.The jewelry retailer's 4th edition of Malabar Gold & Diamonds Festival in the GCC ...

more...


 






Google

Electronic & Mobile Payment

 
 

Middle East North Africa - Financial Network

MENAFN News Market Data Countries Tools Section  
 

Middle East North Africa - Financial Network
Arabic MENAFN

Main News
News By Industry
News By Country

Islamic Finance News
Private Equity News

How-To Guides
Technology Section

Travel Section

Search News

Market Indices
Quotes & Charts

Global Indices
Arab Indices

Commodoties

Oil & Energy

Currencies Cross Rates
Currencies Updates
Currency Converter

USA Stocks
Arab Stocks
 

Algeria 
Bahrain 
Egypt 
Iraq
Jordan 
Kuwait 
Lebanon
Morocco 
Oman 
Palestine
Qatar 
Saudi Arabia 
Syria
Tunisia 
UAE 
Yemen

Weather
Economic Calendar
Financial Glossary


Financial Calculators

RSS Feeds [XML]

Corporate Monitor

Events

Real Estate
Submit Your Property

Arab Research
Buy a Research

Press Releases
Submit your PR

Join Newsletters


 
© 2014 menafn.com All Rights Reserved.  Terms of Service | Privacy Policy | Contact Us | Advertise | About MENAFN | Career Opportunities | Feedback | Help