Quotes: MENA   Enter Symbol: NewsLetter: Search: advanced

New study shows how stem cells could be used in facial reconstruction  Join our daily free Newsletter

MENAFN Press - 13/03/2014
No. of Ratings : 0
Add to Mixx!



(MENAFN Press) The effectiveness of human stem cell therapies for facial reconstruction has been investigated in a new study led by Great Ormond Street Hospital (GOSH) and the UCL Institute of Child Health (ICH)



The paper, published in the journal Nanomedicine, shows how stem cells could pose a viable alternative to current approaches to facial cartilage reconstruction such as ear and nose reconstruction.



GOSH has an excellent track record of successfully treating patients born with a malformed or missing ear, a condition known as microtia. The two-stage ear reconstruction takes cartilage from the patient's ribs and from this, a new scaffold is moulded and placed beneath the skin.



Both the clinical and cosmetic results of this procedure have been very good. However, as Patrizia Ferretti, Head of Developmental Biology Unit at the ICH and her co-authors demonstrate in their study, the potential application of human stem cells and tissue engineering could further improve results and would obviate the need for this invasive part of the procedure, which leaves a permanent defect in the donor site.



Dr Ferretti explains, "We used stem cells (hADSCs) harvested from the abdominal tissue of young patients affected by craniofacial conditions to explore, in our laboratories, how these might be used in future surgery. The use of stem cells from the paediatric patients themselves circumvents the issue of rejection and would overcome the need for immunosuppressive therapies.



The study suggests that combining hADSC with POSS-PCU bionano scaffolds can be of great value for several applications. In addition to ear and nose cartilage reconstruction, they could be used, for example, to improve the quality of tracheal transplants.



Scaffold cellularization in vivo (within the body) is a lengthy and uneven process. Hence POSS-PCU scaffolds pre-seeded with autologous hADSCs could help to improve stability, integration and functionality of engineered transplants while avoiding tissue rejection



Neil Bulstrode, Consultant Plastic Surgeon at GOSH and an author on the paper said: "It is such an exciting prospect with regard to the future treatment of these patients and many more. Currently I take the rib cartilage from the chest to make an ear but if we could produce a block of cartilage using stem cells and tissue engineering, this would be the Holy Grail for our field.



GOSH has one of the largest and most experienced paediatric plastic and reconstructive surgery centres anywhere in the world, with the aim of providing clinical excellence in our special areas of expertise which include; craniofacial surgery, cleft lip and palate repair, congenital hand anomalies, ear surgery, vascular anomalies and birthmarks and general plastic and reconstructive surgery



Note to editor



Great Ormond Street Hospital for Children is one of the world's leading centres for treating sick children, with the widest range of specialists under one roof in the UK



With the UCL Institute of Child Health, we are the largest centre for paediatric research outside the US, and play a key role in training children's health specialists for the future



Great Ormond Street Hospital for Children treated over 1400 inpatients and over 9000 outpatients from the Middle East in 2012/13


About Great Ormond Street Hospital for Children
Great Ormond Street Hospital for Children is one of the world's leading centres for treating sick children, with the widest range of specialists under one roof in the UK.With the UCL Institute of Child Health, we are the largest centre for paediatric research outside the US, and play a key role in training children's health specialists for the future.Great Ormond Street Hospital for Children treated over 1400 inpatients and over 9000 outpatients from the Middle East in 2012/13.

 


MENAFN Press




  MENA News Headlines
 Dec 18 2014 - First Etihad superjumbo to take off next weekAFP
(MENAFN - AFP) The maiden flight of Etihad Airways' long-awaited Airbus A380 superjumbo will take place next week, the Abu Dhabi carrier said Thursday, also announcing its first Boeing 787 Dreamliner ...

 Dec 18 2014 - Saudi crude oil exports grow to 6.9m bpd in Oct.MENAFN
(MENAFN) Top oil exporter Saudi Arabia shipped more crude oil in October than a month earlier while volumes used by domestic refineries remained high allowing more oil products exports, official data ...

 Dec 18 2014 - MEA ICT spending to hit USD270b in 2015MENAFN
(MENAFN) According to a recent report by International Data Corporation (IDC), the Middle East and Africa spending on information and communications technology (ICT) is expected to register a growth ...

 Dec 18 2014 - Expo 2020 to generate USD37.83b in revenue for DubaiMENAFN
(MENAFN) The UAE Ministry of Economy said that it expects the Expo 2020 to bring financial returns of about USD37.83 billion to Dubai, as well as attract more than 25 million visitors, 70 percent of ...

 Dec 18 2014 - Qatar Airways to boost Oman's Salalah serviceMENAFN
(MENAFN) Qatar Airways announced it is planning to add four new services to Salalah, Oman's second largest city, by next February, thus bringing the number of its flights to the city to eight weekly ...

 Dec 18 2014 - Abraaj , Kellogg bidding war intensifies over Egypt's Bisco MisrMENAFN
(MENAFN) The bidding war between UAE's Abraaj Investment Management and Kellogg Co, the breakfast cereal maker, with each company continuously outbidding the other for the acquisition of Egypt's ...

 Dec 18 2014 - UAE's ME Digital Group acquires CoboneMENAFN
(MENAFN) Middle East Digital Group, the online publishing, content and services company and owner of Expatwoman.com, announced it has acquired the online coupon website Cobone in a multi-million ...

 Dec 18 2014 - Dubai's real estate to lead economic growth in 2015MENAFN
(MENAFN) Dubai's Department of Economic Development said that it expects real estate and construction will likely drive economic growth in 2015, which is expected to grow 4.5 percent next year ...

 Dec 18 2014 - Oman's Orpic to invest USD3.6b on increasing productionMENAFN
(MENAFN) Oman Oil Refineries and Petroleum Industries Company (Orpic) announced that its production capacity of polypropylene and polyethylene will increase to 1.4 million tons, when its USD3.6 ...

 Dec 18 2014 - Qatar- HH the Emir, HH the Father Emir Attend National Day Parade -1Qatar News Agency
(MENAFN - QNA) The parade started with the national anthem and the firing of 18-shot gun to celebrate the National Day, followed by a recitation of verses from the Holy Quran. The parade included ...

more...


 






Google

 
 

Middle East North Africa - Financial Network

MENAFN News Market Data Countries Tools Section  
 

Middle East North Africa - Financial Network
Arabic MENAFN

Main News
News By Industry
News By Country

Islamic Finance News
Private Equity News

How-To Guides
Technology Section

Travel Section

Search News

Market Indices
Quotes & Charts

Global Indices
Arab Indices

Commodoties

Oil & Energy

Currencies Cross Rates
Currencies Updates
Currency Converter

USA Stocks
Arab Stocks
 

Algeria 
Bahrain 
Egypt 
Iraq
Jordan 
Kuwait 
Lebanon
Morocco 
Oman 
Palestine
Qatar 
Saudi Arabia 
Syria
Tunisia 
UAE 
Yemen

Weather
Economic Calendar
Financial Glossary


Financial Calculators

RSS Feeds [XML]

Corporate Monitor

Events

Real Estate
Submit Your Property

Arab Research
Buy a Research

Press Releases
Submit your PR

Join Newsletters


 
© 2014 menafn.com All Rights Reserved.  Terms of Service | Privacy Policy | Contact Us | Advertise | About MENAFN | Career Opportunities | Feedback | Help